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Testosterone vs Clomid vs Enclomophene

Testosterone vs. Clomid vs. Enclomiphene

Testosterone Therapy (TRT)

  • Directly increases testosterone
  • May suppress LH/FSH → reduced sperm production
  • Helps muscle, libido, mood

Clomid (Clomiphene)

  • Stimulates brain to release LH/FSH → natural T production
  • Preserves fertility
  • May cause mood swings or vision issues

Enclomiphene

  • Isolated active isomer of Clomid
  • Fewer side effects
  • Preferred for boosting T while maintaining fertility

Can You Combine Them? Not generally advisable. TRT suppresses natural production, which Clomid/Enclomiphene tries to stimulate. They counteract each other. Choose one path based on goals (fertility vs. symptom relief).

Supportive Supplements

  • Zinc, magnesium, vitamin D, omega-3s
  • Liver support (if on oral agents)


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