Perimenopause
Perimenopause is the transitional phase leading up to menopause, typically beginning in a woman’s late 30s to mid-40s and lasting anywhere from 2 to 10 years.
During this time, the ovaries gradually begin to produce less estrogen and progesterone, leading to hormonal fluctuations that can significantly impact physical, emotional, and mental health.
What’s Happening in the Body During Perimenopause?
- Estrogen and progesterone levels become erratic, causing imbalances
- Ovulation becomes irregular, impacting menstrual cycles and fertility
- FSH (follicle-stimulating hormone) levels rise as the ovaries become less responsive
- Testosterone levels may decline, contributing to fatigue, low libido, and muscle loss
Common Symptoms of Perimenopause
Emotional & Cognitive Symptoms, Irregular or heavy periods, Mood swings, anxiety, depression
Hot flashes, night sweats, Brain fog, poor concentration, memory lapses, Sleep disturbances, insomnia, Irritability or emotional sensitivity, Breast tenderness, Low libido or sexual discomfort
Vaginal dryness, Decreased motivation or self-esteem, Weight gain (especially belly fat)
Increased fatigue or burnout, Hair thinning or dry skin, Loss of confidence or emotional detachment
How Perimenopause Affects Daily Life
- Sleep disruption leads to fatigue, brain fog, and poor productivity
- Mood swings or anxiety can strain relationships and mental health
- Irregular cycles may cause embarrassment or social limitations
- Weight gain and low libido can impact self-image and intimacy
- Decreased resilience may reduce confidence and decision-making
Treatment Options for Perimenopause
Bioidentical Hormone Therapy (HRT)
- Progesterone: Improves sleep, reduces anxiety, supports cycle regulation
- Estrogen: Reduces hot flashes, vaginal dryness, and mood symptoms
- Testosterone: May support libido, mood, and energy
Formulations may include creams, capsules, patches, or pellets.
Non-Hormonal Medications
- SSRIs or SNRIs for mood or hot flashes (if hormones are contraindicated)
- Gabapentin or clonidine for hot flashes/night sweats
- Sleep aids (temporary use)
Natural Supplements for Perimenopause
SupplementBenefitVitex (Chasteberry)Supports progesterone and cycle balance
Maca RootImproves energy, mood, and libido
AshwagandhaReduces stress and balances cortisol
Black Cohosh eases hot flashes and night sweats
Evening Primrose Oil Hormonal skin and breast tenderness support5-HTP or L-theanine
Supports mood, sleep, and anxiety
Vitamins & Minerals to Optimize During Perimenopause
Vitamin D3 for Bone health, immune support, hormone balance
Magnesium glycinate for Sleep, mood, muscle relaxation
Vitamin B6 + B12 for Energy, neurotransmitter support, reduces fatigue
Omega-3 fatty acids (DHA/EPA) Anti-inflammatory, mood and skin support
Zinc + SeleniumThyroid support, immunity, and hormone balance
Iron or Ferritin support Important if heavy bleeding is present
Perimenopause is a natural but often misunderstood stage of life. The hormonal shifts can be overwhelming, but personalized care, including lifestyle support, lab-guided supplementation, and hormone therapy when appropriate, can help women thrive—not just survive—during this transition.
