Functional ....
Natalia Poleschuk • June 13, 2025
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Functional Medicine Plan
🔹 1. Glycemic & Lipid Control
- Diet:
- Low-glycemic, Mediterranean-style or low-carb (50–80g/day) until HbA1c <6.0%
- Emphasize: fiber (30g+), omega-3s, cruciferous vegetables, anti-inflammatory foods
- Supplements:
- Berberine 500 mg BID
- Alpha-lipoic acid 300–600 mg/day
- Omega-3s (EPA/DHA 2–4g/day)
- Ceylon cinnamon or gymnema
- Niacin (inositol hexanicotinate) or red yeast rice (if no statin)
Testosterone & SHBG Optimization
- Lifestyle:
- Strength training 3x/week
- Reduce alcohol, optimize sleep
- Labs to add: Estradiol (E2), LH/FSH, prolactin, DHEA-S
- Supplements:
- Zinc 25–50 mg/day (watch copper)
- Vitamin D3 5000 IU/day + K2
- Boron 3–6 mg/day
- Ashwagandha or Tongkat Ali
🔹 3. Iron & Anemia
- Possible causes: Malabsorption, GI loss, frequent donation, poor intake
- Replete with:
- Iron bisglycinate 25–50 mg/day with vitamin C
- Check reticulocyte count, TIBC, and stool for occult blood
- Add B6 and copper if repletion is slow
🔹 4. Cardiovascular Support
- Methylation Support (if homocysteine is high or if MTHFR variants suspected):
- Methyl B12, 5-MTHF, P5P
- Additional:
- CoQ10 100–200 mg/day
- Magnesium glycinate 300–400 mg/day
- Citrulline malate or beetroot for nitric oxide support
🔹 5. Detoxification & Mitochondria
- Support Phase I/II liver detox:
- Milk thistle, NAC, DIM, calcium D-glucarate
- Mitochondrial nutrients:
- PQQ, acetyl-L-carnitine, CoQ10, methylene blue (under guidance)
🔹 6. Peptides (advanced/integrative)
- BPC-157: Gut, vascular & metabolic support
- Thymosin alpha-1: Immune modulation
- CJC-1295/Ipamorelin: Support endogenous GH if fatigue, belly fat present
🔹 7. Lifestyle Tools
- HBOT: Especially useful for diabetes, wound healing, neuroprotection
- Red light therapy: Daily for mitochondria, mood, testosterone
- Sauna therapy: 3–5x/week for insulin and cardiovascular support
- Walking after meals: Lowers glucose and triglycerides
✅ Follow-Up Labs (in 3–6 months)
- Lipids, A1c, iron panel, Vitamin D
- Testosterone panel w/ estradiol & LH/FSH
- hs-CRP
- Homocysteine
- Optional: Gut health panel (if GI concerns), microalbumin/Cr ratio again