Tox Complete Pannel
This test combines the Total Mycotoxin Panel, Organic Acids Panel, Environmental Pollutant Profile, and Glyphosate Exposure Analysis. It detects 16 different mycotoxins and glyphosate, assesses nutritional status, and defines a patient's toxic burden.
comprehensive urine-based Organic Acids and Mycotoxin Panel, which evaluates:
- Mitochondrial function
- Detoxification
- Neurotransmitter metabolism
- Microbial overgrowth
- Oxidative stress
This test measures:
🧬 1. Mitochondrial Function & Krebs Cycle
Indicates how efficiently the body generates energy (ATP).
MarkerFunctionCitric Acid, Isocitric Acid, Cis-Aconitic Acid, Succinic Acid, Fumaric Acid, Malic Acid, Pyruvic Acid, a-Ketoglutaric AcidKrebs (citric acid) cycle intermediates – ↓ or ↑ suggests mitochondrial dysfunction or nutrient cofactor need (e.g., B2, B3, Mg)HydroxymethylglutarateCoQ10 synthesis marker – ↑ = CoQ10 deficiencyMethylsuccinic Acid, Ethylmalonic AcidFatty acid oxidation/metabolism dysfunctionSuberic Acid, Adipic AcidLipid peroxidation / fatty acid metabolismTricarballylic AcidMitochondrial toxin – often from mycotoxins or pesticides
🧠 2. Neurotransmitter Metabolism
Evaluates dopamine, serotonin, and tryptophan pathways.
MarkerFunctionHVA (Homovanillic Acid)Dopamine breakdownVMA (Vanillylmandelic Acid)Norepinephrine/epinephrine metabolism5-HIAA (5-Hydroxyindoleacetic Acid)Serotonin breakdownKynurenic Acid, Quinolinic AcidTryptophan → kynurenine pathway; ↑ Quinolinic = neuroinflammation risk
🍽️ 3. Amino Acid & BCAA Metabolism
Helps assess B-vitamin status and metabolic imbalances.
MarkerFunction3-Hydroxyisovaleric AcidBiotin deficiency markera-Ketoisocaproic, a-Ketoisovaleric, a-Keto-β-methylvaleric acidsBranched-chain amino acid catabolism (leucine, isoleucine, valine)MMA (Methylmalonic Acid)Vitamin B12 deficiency markerOrotic AcidUrea cycle / ammonia detox – ↑ = dysbiosis or protein overload
🦠 4. Gut Dysbiosis & Microbial Metabolites
Reflects abnormal gut flora, yeast/fungal overgrowth, or impaired GI detox.
MarkerFunction3-Indoleacetic AcidTryptophan metabolite – from gut bacteria4-Hydroxybenzoic, 4-Hydroxyphenylacetic, 4-HydroxyphenyllacticClostridia or yeast overgrowthBenzoic Acid, Hippuric AcidDetox of phenols, microbial byproductsPhenylglyoxylic Acid, Mandelic AcidAromatic compound processing – may reflect solvent exposure or dysbiosis
☣️ 5. Environmental Toxins & Solvent Markers
MarkerFunctionMonoethyl Phthalate, PhthalatesPlasticizer metabolites – endocrine disruptorst,t-Muconic AcidBenzene exposure markerPhenylglyoxylic AcidSolvent exposure (e.g., styrene, toluene)GlyphosateHerbicide (Roundup) exposure – disrupts gut and metabolism
🦠 6. Mycotoxins (Mold Exposure)
MarkerFunctionAflatoxins (B1, B2, G1, G2)Carcinogenic mold toxins – commonly from grains, peanutsOchratoxin ANephrotoxic mold toxin – common in water-damaged buildingsZearalenoneEstrogenic mold toxin – food contamination riskRoridin A, E, H, L-2; Satratoxin G, H; Verrucarin A, JTrichothecene toxins – neurotoxic, immunosuppressiveGliotoxin DerivativeImmune-suppressing mold toxin – common in Aspergillus exposureIsosatratoxin FNeurotoxic compound from Stachybotrys ("black mold")
🔥 7. Detoxification, Glutathione, and Antioxidant Demand
MarkerFunctionPyroglutamic AcidGlutathione recycling – ↑ = glutathione depletionLactic AcidAnaerobic metabolism or gut imbalance2-Hydroxybutyric AcidLinked to glutathione production – ↑ in oxidative stress, insulin resistance2-Hydroxyisobutyric AcidSolvent exposure or metabolic disruption
✅ Summary: Why These Markers Matter
This panel gives insight into:
- Energy production (mitochondrial health)
- Nutrient deficiencies (B12, biotin, CoQ10)
- Toxic burden (mold, chemicals, plastics)
- Gut health (dysbiosis, yeast, Clostridia)
- Neurotransmitter balance (dopamine, serotonin)
- Detox capacity (glutathione status, oxidative stress)
Biomarkers:
